Wesley Combs
AI Transformation Leader & Futurist
Product • Engineering • Entrepreneurship • Strategy
“Everyday I try to figure out a way to change healthcare for the better.”
Led NextGen to ship the first Ambient AI on mobile EHR. Now building Phiniti.ai & Ambient Scribe—giving clinicians back their time with patients through AI.
Solving Problems That Matter
A compassionate leader who believes technology should serve humanity, not replace it.
Fun, future-oriented, compassionate leader that loves to solve problems.
Based in Kingsport, Tennessee, I've spent over two decades driving AI transformation across healthcare, finance, supply chain, and eCommerce. Equal parts product leader, engineer, entrepreneur, and business strategist, my journey has been driven by one core belief: technology should amplify human connection, not diminish it.
I see a future where physicians can truly focus on their patients, and where people genuinely engage in their health to extend their time to experience this gift we've been given. Through Phiniti.ai and Ambient Scribe, I'm building the AI tools to make that vision a reality—giving clinicians back their most precious resource: time with patients.
My career includes 10+ years as CIO at Holston Medical Group, building OnePartner into a platform serving 3M+ lives, and bringing ambient clinical documentation to market at NextGen Healthcare. When I'm not disrupting healthcare, you'll find me serving my community through Kingsport Kiwanis or spending time with my wife Rebecca and our two daughters.
Education
Executive MBA
UT Knoxville - Haslam College of Business
B.S. Computer Science
East Tennessee State University
Innovation
Building the future of healthcare
Compassion
Technology that serves humanity
Career Highlights
25+ years of building, leading, and transforming—from the earliest days of healthcare interoperability to today's AI revolution.
OnePartner Platform
$180M+ Medicare Savings
Built the population health platform that powered two ACOs to 10 consecutive years of positive performance. Generated $76M+ in earned shared savings.
NHIN Pioneer
National Health Information Network
Contributed to the NHIN1/NHIN2 proof-of-concept pilots under David Brailer, the first National Health IT Coordinator appointed by President George W. Bush in 2004. Early architect of nationwide healthcare interoperability.
NextGen Healthcare
First Ambient AI on Mobile EHR
Led NextGen to become the first EHR vendor to ship Ambient AI on mobile (November 2023). Managed $320M product portfolio across EHR, Mobile, and EHR Content.
Lucent Glow
Founded & Exited
Founded healthcare IT consulting company in 2004, grew from sole proprietor to 10 employees, and successfully exited via sale in 2011. Built HL7/CCD interfaces during healthcare IT's formative years.
Building the Future of Healthcare
Two companies, one mission: harmonizing clinicians with technology to improve patient outcomes.
AI-Powered Healthcare Intelligence
Enterprise AI platform transforming healthcare operations through intelligent automation, predictive analytics, and decision support systems.
Voice-First Clinical Documentation
Revolutionary ambient listening technology that captures patient encounters naturally, generating accurate clinical notes while providers focus on what matters—their patients.
We're product-driven and user-focused. We ship PRs daily, implement features in days not months, and deeply appreciate every piece of feedback. Convenience in the clinical workflow is our north star.
Awards & Leadership
A decade of recognized impact in healthcare technology and community service.
Beta Tech Accelerator
LatestSelected for elite healthcare technology accelerator program
Healthcare Hero
Recognized for outstanding contributions to healthcare innovation in the Tri-Cities region
40 Under 40
Tri-Cities Business Journal recognition for exceptional leadership and achievement
Cup of Kindness
Tri-Cities Business Journal award for community service and compassionate leadership
“True leadership isn't about the accolades—it's about the lives you improve and the problems you solve along the way.”
Giving Back
Leadership extends beyond the boardroom. Making a difference in the Tri-Cities community through service and civic engagement.
Kingsport Kiwanis Club
Active Member
Contributing to community service initiatives focused on youth development and local community improvement in the Tri-Cities area.
Board of Zoning Appeals
Board Member
Serving the City of Kingsport by reviewing zoning variance requests and ensuring balanced community development.
First Presbyterian Church
Member
Active participant in the Kingsport faith community, engaging in worship and fellowship with family.
Family First
At the heart of everything is family. Proud husband to Rebecca and father to two wonderful daughters. Rogersville roots with Kingsport community ties.
Let's Start a Conversation
Whether you're interested in healthcare innovation, seeking a speaker, or exploring collaboration opportunities—I'd love to hear from you.
Speaking & Thought Leadership
Available for keynotes, panels, and podcasts on healthcare technology, AI in medicine, entrepreneurship, and reducing clinician burnout.